THE PD-(D/E)XK SUPERFAMILY REVISITED: IDENTIFICATION OF NEW MEMBERS AMONG PROTEINS INVOLVED IN DNA METABOLISM AND FUNCTIONAL PREDICTIONS FOR DOMAINS OF (HITHERTO) UNKNOWN FUNCTION

Abstract Background The PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is one of the most challenging targets for protein sequence analysis and structure prediction.Typically, the sequence similarity between these proteins is so low, that

Researcher behavior is shown to change under assessment.An unexpected time-skew toward most recent papers in each census period was found among the outputs selected by UK academics for the research assessment cycles of the 1990s.This skew changed to a more even time-based distribution for scientists and Clothing engineers in later cycles.At the sam

Ring signcryption with no group administrator satisfies the decentralization and blockchain anonymity.In this article, we construct new lattice-based ring signcryption scheme suitable for consortium blockchain (CB-LRSCS), in which the smart Hair Coloring contract controls the process of signcryption and unsigncryption to make the system be fair and

The explosion of non-structured materials science data makes it urgent for materials researchers to resolve the problem of Fridge Thermostat how to effectively share this information.Materials science image data is an important class of non-structured data.This paper proposes a semantic annotation method to resolve the problem of materials science

Towards addressing ontological issues in design cognition research, this paper presents the first generic classification of cognitive processes investigated in protocol studies on conceptual design cognition.The classification is based on a systematic review of 47 studies published over the past 30 years.Three viewpoints on the nature of design cog